The Moderate-dose Group Received A Capsule Containing 12.5 Milligrams Of Thc, Which Comes Closer To Half A Joint.  The Placebo Group Received A Capsule Containing No Thc.  Neither The Participants Nor The Researchers Knew Who Was In Each Group.

Medical marijuana alt=’MailOnline iPad app’ /> The low-dose group received a capsule containing 7.5 milligrams of THC, which is equivalent to one or two puffs on a medical-grade joint. The moderate-dose group received a capsule containing 12.5 milligrams of THC, which comes closer to half a joint.  The placebo group received a capsule containing no THC.  Neither the participants nor the researchers knew who was in each group. ‘The doses used in the study produce effects that are equivalent to only a few puffs of a cannabis cigarette,’ said Childs, noting that it is difficult to compare doses of smoked cannabis to doses of ingested THC.  ‘We didn’t want to include a much larger dose, because we wanted to avoid potential adverse effects or cardiovascular effects that can result from higher doses of THC.’ Participants attended two four-hour sessions at the University of Chicago, five days apart.  Cannabidiol (CBD) is a drug derived from cannabis. The medicine has the psycho-active elements of marijuana, THC, removed. THC is what gives marijuana users their ‘high’. The drug offers hope for thousands of children living with untreatable epilepsy. Cannabidiol halved the seizures suffered by children with a severe form of the condition called Dravet syndrome.  Experts at New York University and Great Ormond Street children’s hospital in London said the results could make a ‘considerable difference’ to adults and children suffering with epilepsy.  In five percent of patients given the oil the debilitating fits stopped altogether.  At each session, they took their capsule and then relaxed for two hours to allow the THC to be absorbed into the bloodstream. During one session, participants were asked to spend 10 minutes preparing for a mock job interview.  They were then subjected to a five-minute interview with lab assistants who did not offer any feedback, verbally or through body language, although video display was visible to the participant, showing their performance.  Participants were then instructed to count backwards from a five-digit number by subtracting 13, for five minutes—a task that is ‘very reliably stress-inducing,’ Childs said. In their second visit, participants were asked to talk to lab assistants about a favorite book or movie for five minutes and then play solitaire for another five minutes. Before, during and after each of the two activities, participants rated their stress levels and feelings about the tasks. Blood pressure, heart rate, and cortisol, a key stress hormone, were measured at intervals.

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